On May 20, 2021, the IV Annual All-Russian Scientific and Practical Conference with international participation "SAFETY OF PHARMACOTHERAPY: NOLI NOCERE!" was held at the Kazan State Medical Academy. The conference was attended by more than 300 people, including residents, postgraduates and young scientists, doctors, professors of Russian and foreign universities. The objectives of the conference were to update the issues of clinical pharmacology, safety of pharmacotherapy, pharmacovigilance, evidence-based medicine.